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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK14 All Species: 23.94
Human Site: S122 Identified Species: 40.51
UniProt: O94921 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94921 NP_036527.1 469 53057 S122 V R R H S S P S S P T S P K F
Chimpanzee Pan troglodytes XP_519189 469 53035 S122 V R R H S S P S S P T S P K F
Rhesus Macaque Macaca mulatta XP_001102520 469 53072 S122 V R R H S S P S S P T S P K F
Dog Lupus familis XP_532455 469 53036 S122 V R R H S S P S S P T S P K F
Cat Felis silvestris
Mouse Mus musculus O35495 469 52977 S122 V R R H S S P S S P T S P K F
Rat Rattus norvegicus O35831 523 59414 A179 M S R R S R R A S L S E I G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516045 337 37621 S35 Q I C V T K M S G R S C P G G
Chicken Gallus gallus XP_418647 773 84016 S426 V R R H S S P S S P T S P K F
Frog Xenopus laevis Q6DJM7 435 49211 L107 S Y E K L E K L G E G S Y A T
Zebra Danio Brachydanio rerio Q1RLU9 418 47889 L109 I S R I N G H L V A L K V I H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523904 522 59750 A192 P R R K R F S A F G G D S P F
Honey Bee Apis mellifera XP_624994 494 56118 A152 R R T K R F S A F G G D S P F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P24100 294 34012
Baker's Yeast Sacchar. cerevisiae P17157 305 34888
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 99.7 99.1 N.A. 98.5 43 N.A. 60.7 58.5 85.2 51.5 N.A. 48.4 50 N.A. N.A.
Protein Similarity: 100 99.5 99.7 100 N.A. 99.3 59 N.A. 63.3 59.5 89.3 63.1 N.A. 61.2 63.3 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 26.6 N.A. 13.3 100 6.6 6.6 N.A. 20 13.3 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 46.6 N.A. 26.6 100 6.6 20 N.A. 26.6 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.7 28.5 N.A.
Protein Similarity: N.A. N.A. N.A. 42.8 43.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 22 0 8 0 0 0 8 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 % D
% Glu: 0 0 8 0 0 8 0 0 0 8 0 8 0 0 0 % E
% Phe: 0 0 0 0 0 15 0 0 15 0 0 0 0 0 65 % F
% Gly: 0 0 0 0 0 8 0 0 15 15 22 0 0 15 8 % G
% His: 0 0 0 43 0 0 8 0 0 0 0 0 0 0 8 % H
% Ile: 8 8 0 8 0 0 0 0 0 0 0 0 8 8 0 % I
% Lys: 0 0 0 22 0 8 8 0 0 0 0 8 0 43 0 % K
% Leu: 0 0 0 0 8 0 0 15 0 8 8 0 0 0 0 % L
% Met: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 0 0 0 0 43 0 0 43 0 0 50 15 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 58 65 8 15 8 8 0 0 8 0 0 0 0 0 % R
% Ser: 8 15 0 0 50 43 15 50 50 0 15 50 15 0 0 % S
% Thr: 0 0 8 0 8 0 0 0 0 0 43 0 0 0 8 % T
% Val: 43 0 0 8 0 0 0 0 8 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _